Pyridine- and quinoline-pyrimidine-derivatives

Details Pyridine- and quinoline-pyrimidine-derivatives Pyridine- and quinoline-pyrimidine-derivatives

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4427 (2006.01) A61P 1/18 (2006.01)

Patent

CA 2662099

This invention is concerned with compounds of the formula (I) wherein A, R1 to R5 are as defined in the specification and G is a pyridine, quinoline or pyrimidine group as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.

La présente invention concerne des composés, ou certains de leurs sels pharmaceutiquement admis, représentés par la formule (I) dans laquelle A, R1 à R5 sont tels que définis dans la spécification et G est un groupe pyridine, quinoline ou pyrimidine tel que défini dans la spécification. L'invention concerne également des compositions pharmaceutiques contenant de tels composés, des procédés d'élaboration correspondant, et leur utilisation pour le traitement et/ou la prévention de maladies associées à la modulation du sous-type 5 des récepteurs SST.

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