Modulating the activity of hormones or their receptors -...

Details Modulating the activity of hormones or their receptors -... Modulating the activity of hormones or their receptors -...

C - Chemistry, Metallurgy

07

K

C07K 14/575 (2006.01) A61K 38/22 (2006.01) A61K 38/31 (2006.01) A61K 39/00 (2006.01) A61K 39/385 (2006.01) A61K 39/39 (2006.01) C07K 14/47 (2006.01) C07K 14/655 (2006.01) C07K 14/72 (2006.01) C07K 16/26 (2006.01) C07K 16/28 (2006.01) C07K 17/02 (2006.01)

Patent

CA 2255888

This invention relates to immunogenic, non-naturally occurring peptides and immunologically reactive molecules thereto which modulate the activity of hormones or the receptors therefor. These peptides are based on portions of somatostatin, somatostatin receptors and insulin-like growth factor binding protein. Methods of modulating hormonal activity in an animal and compositions therefor are also contemplated.

L'invention se rapporte à des peptides immunogènes, que l'on ne rencontre pas à l'état naturel, et à des molécules réagissant immunologiquement avec ces peptides, qui modulent l'activité d'hormones ou de récepteurs d'hormones. Ces peptides sont basés sur des parties de somatostatine, sur des récepteurs de somatostatine et sur une protéine de liaison du facteur de croissance proche de l'insuline. L'invention se rapporte également à des procédés visant à moduler l'activité hormonale chez un animal ainsi qu'à des compositions utilisées à cet effet.

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