Processes for producing sugar nucleotides and complex...

C - Chemistry – Metallurgy – 12 – P

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C12P 19/30 (2006.01) C12P 19/00 (2006.01) C12P 19/26 (2006.01)

Patent

CA 2237849

This invention relates to a process for producing a sugar nucleotide, in which a) a culture broth of a microorganism capable of producing NTP from a nucleotide precursor, or a treated product of the culture broth, and b) a culture broth of a microorganism capable of producing a sugar nucleotide from a sugar and NTP, or a treated product of the culture broth, are used as enzyme sources; a process for producing a complex carbohydrate, in which the above-described a) and b) and c) a culture broth of a microorganism, an animal cell or an insect cell capable of producing a complex carbohydrate from a sugar nucleotide and a complex carbohydrate precursor, or a treated product of the culture broth, are used as enzyme sources; a process for producing a complex carbohydrate, in which a culture broth of a microorganism, an animal cell or an insect cell capable of producing a complex carbohydrate from a sugar nucleotide and a complex carbohydrate precursor, or a treated product of the culture broth, is as an enzyme source; and a process for producing N-acetylglucosamine-1-phosphate, in which a culture broth of a microorganism having strong galactokinase activity, or a treated product of the culture broth, is used as the enzyme source.

Un procédé de production de nucléotides de sucre utilise, comme sources d'enzymes, a) une culture traitée facultativement d'un micro-organisme capable de produire une forme NTP d'un précurseur nucléotidique, b) une culture traitée facultativement d'un micro-organisme capable de produire un nucléotide de sucre à partir d'un sucre et de NTP; un procédé de production de glucides complexes utilise, comme sources d'enzymes, les cultures précitées a) et b), et c) une culture traitée facultativement d'un micro-organisme, des cellules animales ou des cellules d'insectes capables de produire un glucide complexe à partir d'un nucléotide de sucre et d'un précurseur de glucides complexes; un procédé de production de glucides complexes utilise, comme source d'enzymes, une culture traitée facultativement d'un micro-organisme, des cellules animales ou des cellules d'insectes capables de produire un glucide complexe à partir d'un nucléotide de sucre et d'un précurseur de glucides complexes; et un procédé de production de N-acétylglucosamine-1-phosphate utilise, comme source d'enzymes, une culture traitée facultativement d'un micro-organisme présentant une puissante activité galactokinase.

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