Use of antiprogestins for prophylaxis and treatment of...

A - Human Necessities – 61 – K

Patent

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A61K 31/567 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2423017

The present invention relates to methods and uses for preventing or treating hormone-dependent disease, in particular breast cancer, in a mammal by antiprogestins, in particular antiprogestin 11.beta.-(4-acetylphenyl)-17.beta.- hydroxy-17.alpha.-(1,1,2,2,2-pentafluoroethyl)-estra-4,9-dien-3-one or a pharmaceutically acceptable derivative or analogue thereof. The invention further relates to pharmaceutical compositions comprising said antiprogestin.

La présente invention concerne des méthodes et des utilisations destinées à prévenir ou traiter, chez un mammifère, des maladies dépendant des hormones, et notamment le cancer du sein, au moyen d'antiprogestines telles que l'antiprogestine 11.beta.-(4-acétylphényl)-17.beta.-hydroxy-17.alpha.-(1,1,2,2,2-pentafluoroéthyl)-estra-4,9-diène-3-one ou d'un dérivé pharmaceutiquement acceptable ou analogue dudit composé. L'invention se rapporte en outre à des compositions pharmaceutiques renfermant cette antiprogestine.

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