Human protein kinases

Details Human protein kinases Human protein kinases

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A61K 38/45 (2006.01) C07K 16/40 (2006.01) C12N 9/12 (2006.01) C12Q 1/48 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2264541

The present invention provides novel human protein kinases (HPK) and polynucleotides which identify and encode HPK. The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HPK. The invention also provides for pharmaceutical compositions comprising HPK or antagonists of HPK, and antibodies which specifically bind HPK. Additionally, the invention provides antisense molecules to HPK for treatment or prevention of diseases associated with abnormal expression of HPK.

L'invention porte sur de nouvelles protéines kinases humaines (HPK) et sur des polynucléotides identifiant et codant pour le HPK. L'invention porte également sur des vecteurs et cellules hôtes d'expression comportant les séquences d'acide nucléique codant pour le HPK, sur des préparations pharmaceutiques comprenant le HPK ou ses antagonistes et sur des anticorps se fixant spécifiquement au HPK. Elle porte en outre sur des molécules antisens du HPK servant à traiter ou prévenir les maladies associées à l'expression anormale du HPK.

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