Hydroxylamine and oxime substituted imidazoquinolines,...

Details Hydroxylamine and oxime substituted imidazoquinolines,... Hydroxylamine and oxime substituted imidazoquinolines,...

A - Human Necessities

61

K

A61K 31/44 (2006.01) A61K 31/42 (2006.01) C07D 471/02 (2006.01) C07D 471/06 (2006.01)

Patent

CA 2547085

Imidazo-quinoline, -pyridine, and -naphthyridine ring systems substituted at the 1-position, pharmaceutical compositions containing the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.

La présente invention a trait à des système cycliques d'imidazo-quinoléine, d'imidazo-pyridine, et d'imidazo naphtyridine substitués en position 1, des compositions pharmaceutiques contenant les composés, des intermédiaires, et des procédés d'utilisation de ces composés en tant qu'immunomodulateurs, pour l'induction de la biosynthèse de cytokines chez des animaux et dans le traitement de maladies virales et néoplasiques.

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