Crystal structure of 3',5'-cyclic nucleotide...

Details Crystal structure of 3',5'-cyclic nucleotide... Crystal structure of 3',5'-cyclic nucleotide...

C - Chemistry, Metallurgy

12

N

C12N 9/16 (2006.01)

Patent

CA 2558213

Crystal structure of phosphodiesterase 10A (PDE10A), and the 3-D atomic coordinates of the PDE10A binding domain, as described and used for the identification of ligands, including PDE10A inhibitors, used to treat various psychological disorders.

L'invention concerne la structure cristalline de la phosphodiestérase 10A (PDE10A), et les coordonnées atomiques 3 D du domaine de liaison PDE10A, et ses utilisations pour l'identification de ligands, y compris des inhibiteurs PDE10A utilisés pour traiter divers troubles psychologiques.

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