Monoclonal antibody reactive with a novel hla determinant on...

Details Monoclonal antibody reactive with a novel hla determinant on... Monoclonal antibody reactive with a novel hla determinant on...

C - Chemistry, Metallurgy

12

P

167/139, 195/1.1

C12P 21/08 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2038397

PATENT 6988 ABSTRACT OF THE INVENTION The present invention relates to novel monoclonal antibody 4-10 produced by hybridoma ATCC No. HB10355 and its use in the activation of lymphocytes, particularly T cells. Monoclonal antibody 4-10 activates T cells without requiring co-stimulatory agents. The antibody, methods and compositions of this invention are useful in the activation of lymphocytes and in treating immune diseases. 6988APL.2

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