N-`4-(2-imino-pyrrolidin-1-yl)phenyl!-acetamide and...

Details N-`4-(2-imino-pyrrolidin-1-yl)phenyl!-acetamide and... N-`4-(2-imino-pyrrolidin-1-yl)phenyl!-acetamide and...

C - Chemistry, Metallurgy

07

D

C07D 453/06 (2006.01) A61K 31/402 (2006.01) A61K 31/439 (2006.01) A61K 31/451 (2006.01) A61K 31/4725 (2006.01) C07D 207/22 (2006.01) C07D 207/24 (2006.01) C07D 211/72 (2006.01) C07D 223/06 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2481026

The invention relates to novel compounds of formula (I) wherein D, M, W, X, Y, T and R1 have the designation cited in patent claim 1. According to the invention, said compounds are inhibitors of the coagulation factor Xa and can be used for the prophylaxis and/or treatment of thromboembolic diseases and for the treatment of tumours.

La présente invention concerne de nouveaux composés de formule (I), dans laquelle D, M, W, X, Y, T et R?1 ¿ont les significations énoncées dans la revendication 1 de cette invention. Ces composés constituent des inhibiteurs du facteur de coagulation Xa et peuvent être utilisés pour prévenir et/ou traiter des maladies thromboemboliques et pour traiter des tumeurs.

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