Promotion of axonal regeneration

Details Promotion of axonal regeneration Promotion of axonal regeneration

A - Human Necessities

61

K

A61K 38/17 (2006.01)

Patent

CA 2576526

The present invention concerns a method of promoting axonal regeneration. In particular, the invention concerns a method of promoting the growth or regeneration of neurons, and treating disease or conditions associated with the loss, loss of function or dysfunction of nerve cells, in particular thalamic nerve cells, by administering a polypeptide having a high degree of sequence identity with a native sequence Netrin G1 (NGL-1) or an agonist thereof.

La présente invention concerne une méthode de promotion de la régénération axonale. L'invention concerne, en particulier, une méthode de promotion de la croissance ou de la régénération des neurones, et de traitement d'une maladie ou d'états pathologiques associés à la perte, à la perte fonctionnelle ou à un dysfonctionnement des cellules nerveuses, en particulier des cellules nerveuses thalamiques, par administration d'un polypeptide présentant un degré élevé d'identité séquentielle avec une séquence native Nétrine G1 (NGL-1) ou un agoniste de celle-ci.

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