Ergoline-8-carboxamides

Details Ergoline-8-carboxamides Ergoline-8-carboxamides

C - Chemistry, Metallurgy

07

D

167/231, 260/273

C07D 457/06 (2006.01) A61K 31/475 (2006.01)

Patent

CA 2040170

X-7844 Abstract of the Disclosure This invention provides N-(2-hydroxycyclo- pentyl)-1-isopropyl-6-methylergoline-8-carboxamides useful for blocking 5HT2 receptors in mammals having an excess of serotonin centrally or peripherally. The invention also provides methods for treating sexual dysfunction, hypertension, migraine, vasospasm, thrombosis, ischemia, depression, anxiety, sleep disorders and appetite disorders with a compound of the invention.

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