2-(pyridin-2-ylamino)-pyrido[2,3-d]pyrimidin-7-ones

Details 2-(pyridin-2-ylamino)-pyrido[2,3-d]pyrimidin-7-ones 2-(pyridin-2-ylamino)-pyrido[2,3-d]pyrimidin-7-ones

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/519 (2006.01) A61K 31/675 (2006.01) A61P 25/00 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 2473026

The present invention provides substituted 2-aminopyridines useful in treating cell proliferative disorders. The novel compounds of the present invention are potent inhibitors of cyclin-dependent kinases 4 ( cdk4 ).

L'invention concerne des 2-aminopyridines substituées servant à traiter des troubles de la prolifération cellulaire. Les nouveaux composés selon l'invention constituent de puissants inhibiteurs des kinases dépendantes des cyclines 4 (cdk4).

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