Small animal metastasis model

A - Human Necessities – 01 – K

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Details

A01K 67/027 (2006.01) A61K 49/00 (2006.01) C12Q 1/02 (2006.01) G01N 33/48 (2006.01)

Patent

CA 2134110

2134110 9420147 PCTABS00033 A method for initiating metastasis of human tumor cells under experimental conditions is provided. Immunocompromised non-human mammals having a viable, xenogeneic organ or tissue are used as a host for human tumor cells. The cells are introduced into the chimeric animal after the solid tissue is implanted and are then able to grow and metastasize as they would in situ. Therapeutic regimens may be evaluated in this system to determine efficacy against metastatic processes.

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