Osmotic delivery system having space efficient piston

Details Osmotic delivery system having space efficient piston Osmotic delivery system having space efficient piston

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 9/24 (2006.01) A61K 9/52 (2006.01)

Patent

CA 2356860

An osmotic delivery system having a space efficient piston. The capsule has an interior holding the piston, a beneficial agent, and an osmotic agent. The piston is movable with respect to an interior surface of the capsule, and defines a movable seal with the interior surface of the capsule. The movable seal separates the osmotic agent from the beneficial agent. The piston has a recess that receives at least a portion of the osmotic agent. The osmotic agent imbibes liquid from a surrounding environment through a semipermeable body to cause the piston to move and in turn cause delivery of the beneficial agent from the capsule.

L'invention concerne un système de distribution osmotique à piston utilisant efficacement l'espace environnant. Une capsule présente un intérieur supportant un piston, un agent bénéfique et un agent osmotique. Ce piston est mobile par rapport à la surface intérieure de la capsule, et définit un joint mobile avec ladite surface intérieure de la capsule. Le joint mobile sépare l'agent osmotique de l'agent bénéfique. Le piston présente un évidement qui reçoit au moins une partie de l'agent osmotique. Ledit agent osmotique s'imbibe de liquide à partir d'un espace environnant par l'intermédiaire d'un corps semi-perméable, ce qui amène le piston à se déplacer, celui-ci provoquant à son tour la distribution de l'agent bénéfique à partir de la capsule.

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