Humanized anti-amyloid antibody

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61P 25/28 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 16/18 (2006.01) C07K 16/46 (2006.01) C12N 15/63 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2589860

Compositions for treating neurodegenerative or amyloidgenic disorders such as Alzheimer's disease (AD) are provided. More particularly, humanized anti- amyloid-beta antibodies, compositions containing such antibodies, corresponding nucleic acids, vectors and host cells, and methods of making such antibodies are provided.

L'invention concerne des compositions destinées à traiter les troubles neurodégénératifs ou amyloïdogéniques, tels que la maladie d'Alzheimer. L'invention concerne plus particulièrement des anticorps anti-amyloïdes bêta humanisés, des compositions contenant ces anticorps, des acides nucléiques correspondants, des vecteurs et des cellules hôtes, ainsi que des procédés de fabrication desdits anticorps.

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