Cells for the production of recombinant adenoviruses

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 7/01 (2006.01) C07K 14/075 (2006.01) C12N 5/10 (2006.01) C12N 7/04 (2006.01) C12N 15/12 (2006.01) C12N 15/34 (2006.01) C12N 15/62 (2006.01) C12N 15/86 (2006.01) C12N 15/861 (2006.01) C12N 15/864 (2006.01)

Patent

CA 2210168

The invention relates to cells usable for the production of defective adenoviruses comprising, inserted into their genome, a portion of the region E4 of an adenovirus genome carrying the reading phase ORF6 under the control of a functional promoter.

L'invention concerne des cellules utilisables pour la production d'adénovirus défectifs comprenant, insérée dans leur génome, une partie de la région E4 d'un génome d'adénovirus portant la phase de lecture ORF6 sous contrôle d'un promoteur fonctionnel.

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