New bicyclic antibiotics

Details New bicyclic antibiotics New bicyclic antibiotics

C - Chemistry, Metallurgy

07

D

C07D 413/14 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2580621

The invention relates to novel antibiotics of formula (I) wherein R1 represents alkyl, alkoxy, haloalkoxy, halogen or cyano; one or two of U, V, W and X represent(s) N, the remaining represent CH, or, in case of U, V and/or W, may also represent CRa and, in the case of X, may also represent CRb; Ra represents halogen; Rb represents halogen or alkoxy; M is a linking chain containing a non-aromatic cyclic or heterocyclic group, and D represents alkyl, aryl or heteroaryl.

La présente invention concerne de nouveaux antibiotiques représentés par la formule (I). Dans cette formule, R1 est alkyle, alcoxy, haloalcoxy, halogène ou cyano; l'un ou deux des U, V, W et X est/sont N, le restant étant CH, mais dans le cas de U, V et/ou W, ce restant peut également être CRa et, dans le cas de X, il peut aussi être CRb; Ra est halogène; Rb est halogène ou alcoxy; M est une chaîne de liaison contenant un groupe hétérocyclique ou cyclique non aromatique, et D étant alkyle, aryle ou hétéroaryle.

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