Formation of medically useful gels comprising microporous...

A - Human Necessities – 61 – K

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A61K 9/10 (2006.01) A61K 9/00 (2006.01) A61K 47/30 (2006.01) A61P 41/00 (2006.01)

Patent

CA 2673646

Compositions and methods use the gel-forming properties of microporous particles to create useful formulations combining two free-flowing materials to produce a hydrogel mass. The free-flowing materials preferably provide dry microporous particles (preferably as an aerosol) that may contain additional agents, and a second composition of a fluid material which is an aqueous solution of one or more high molecular weight polymers capable of forming a hydrogel upon further concentration and/or reaction. The hydrogels can be preferably formed on a surface by spraying the two compositions as fluids together in the proper ratio onto the surface.

L'invention concerne des compositions et des procédés qui utilisent les propriétés gélifiantes de particules microporeuses pour créer des formulations utiles combinant deux matériaux coulants pour produire une masse d'hydrogel. Les matériaux coulants fournissent de préférence des particules microporeuses sèches (de préférence en tant qu'aérosol) qui pouvant contenir des agents additionnels, et une seconde composition d'un matériau fluide qui est une solution aqueuse d'un ou plusieurs polymères à poids moléculaire élevé capable de former un hydrogel lors d'une concentration et/ou d'une réaction supplémentaire. Les hydrogels peuvent être formés de préférence sur une surface en pulvérisant sur ladite surface les deux compositions sous forme de fluides en même temps et dans une proportion appropriée.

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