Assay for chagas' disease and reagents for its use

Details Assay for chagas' disease and reagents for its use Assay for chagas' disease and reagents for its use

C - Chemistry, Metallurgy

07

K

C07K 14/44 (2006.01) A61K 39/005 (2006.01) C07K 1/22 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2139632

An assay to confirm the presence of antibodies to T. cruzi in a test sample. The assay comprises de- tecting the presence of antibody to three T. cruzi anti- gens, Gp90, Gp60/50 and LPPG in a test sample. The presence of antibody in the test sample to at least two of three T. cruzi antibodies is indicative of a con- firmed reactive sample. Also provided are diagnostic reagents for detection of T. cruzi, a process for purify- ing GP60/50, a process for linking a protein and LPPG, and diagnostic test kits for use when assaying for antibodies to T. cruzi.

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