Method of inhibiting gene expression

A - Human Necessities – 61 – K

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A61K 48/00 (2006.01) A61K 31/7088 (2006.01) A61K 31/713 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) C12Q 1/00 (2006.01) C12Q 1/66 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2467936

A method of inhibiting the expression of a target gene which comprises transferring a double-stranded polynucleotide consisting of a DNA having a sequence substantially identical with at least a part of the base sequence of the target gene and RNA into a cell, a tissue or an individual.

La présente invention concerne un procédé pour inhiber l'expression d'un gène cible qui comprend le transfert dans une cellule, dans un tissu ou chez un individu, d'un polynucléotide double brin comprenant un ADN ayant une séquence sensiblement identique à au moins une partie de la séquence de base du gène cible et de l'ARN.

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