Enzymatic disinsertion of vitreous body

Details Enzymatic disinsertion of vitreous body Enzymatic disinsertion of vitreous body

A - Human Necessities

61

K

A61K 38/51 (2006.01)

Patent

CA 2080700

A method for selectively and completely disinserting the ocular vitreous body, epiretinal membranes and/or fibrocellular membranes from the neural retina, ciliary epithelium and posterior lens surface of the mammalian eye as an adjunct to vitrectomy comprises administering to the eye an effective amount of a protease-free glycosaminoglycanase enzyme, such as chondroitinase ABC, adapted to disrumpt and/or degrade chondroitin sulfate glycosaminoglycan/proteoglycan localized specifically to sites of vitreoretinal adhesion and thereby permit complete disinsertion of the vitreous body and/or epiretinal membranes.

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