Methods and compositions for predicting drug responses

Details Methods and compositions for predicting drug responses Methods and compositions for predicting drug responses

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2583904

The present invention relates to methods and compositions for predicting drug responses. In particular, the present invention provides methods and compositions for determining individualized Warfarin dosages based on the presence or absence of polymorphisms in the VKORC1 gene. The present invention further provides methods and compositions for determining individualized Warfarin dosages based on the level of expression of the VKORC1 gene.

L'invention concerne des procédés et des compositions permettant de prédire des réactions à des médicaments. L'invention concerne en particulier des procédés et des compositions permettant de déterminer des doses de warfarine personnalisées en fonction de la présence ou de l'absence de polymorphismes dans le gène VKORC1. L'invention concerne en outre des procédés et des compositions permettant de déterminer des doses de warfarine personnalisées en fonction du niveau d'expression du gène VKORC1.

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