Benzimidazole derivatives as inhibitors of smooth muscle...

C - Chemistry – Metallurgy – 07 – D

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C07D 235/08 (2006.01) A61K 31/415 (2006.01) C07D 235/12 (2006.01) C07D 235/18 (2006.01)

Patent

CA 2223393

Disclosed herein are compounds and pharmaceutically acceptable salts of compounds of formula (I) or (II), wherein R is alkyl, phenyl or substituted phenyl; R2 is hydrogen, halogen, alkoxy or alkyl; R1 is hydrogen, alkyl, aryl, arylalkyl, or substituted benzyl; which are useful as inhibitors of smooth muscle cell proliferation.

Composés et sels pharmaceutiquement acceptables de composés de formule (I) ou (II), dans lesquelles R est alkyle, phényle ou phényle substitué, R¿2? est hydrogène, halogène, alcoxy ou alkyle, R¿1? est hydrogène, alkyle, aryle, arylalkyle ou benzyle substitué. Ces substances sont utiles comme inhibiteurs de la prolifération des cellules musculaires lisses.

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