A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/44 (2006.01) A61K 31/425 (2006.01) A61K 31/445 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/505 (2006.01) A61K 31/53 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 215/02 (2006.01) C07D 237/26 (2006.01) C07D 239/02 (2006.01) C07D 241/36 (2006.01) C07D 249/02 (2006.01) C07D 251/72 (2006.01) C07D 253/10 (2006.01) C07D 261/20 (2006.01) C07D 275/02 (2006.01) C07D 277/20 (2006.01) C07D 285/08 (2006.01) C07D 285/16 (2006.01) C07D 403/14 (2006.01) C07D 409/12 (2006.01) C07D 411/1
Patent
CA 2293400
The present invention relates to novel heteroaryl compounds and the physiologically acceptable salts and the prodrugs thereof which are expected to modulate the activity of protein tyrosine enzymes which are related to cellular signal transduction, in particular, protein tyrosine phosphatase, and therefore are expected to be useful in the prevention and treatment of disorders associated with abnormal protein tyrosine enzyme related cellular signal transduction such as cancer and diabetes.
La présente invention concerne de nouveaux composés hétéroaryle, des sels physiologiquement acceptables et des promédicaments de ceux-ci, destinés à moduler l'activité des enzymes protéine tyrosine qui sont associées à la transduction de signaux cellulaires, en particulier l'activité de la protéine tyrosine phosphatase. Lesdits composés sont donc destinés à être utilisés dans la prévention et le traitement de troubles associés à la transduction anormale de signaux cellulaires associée à des enzymes protéine tyrosine, telle que le cancer et le diabète.
Mcmahon Gerald
Ramphal John Y.
Tang Peng Cho
Smart & Biggar
Sugen Inc.
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