Production for biologically active polypeptide

Details Production for biologically active polypeptide Production for biologically active polypeptide

C - Chemistry, Metallurgy

12

P

C12P 21/00 (2006.01) C07K 14/475 (2006.01) C07K 14/48 (2006.01) C12N 5/06 (2006.01) C12N 5/10 (2006.01) C12N 15/18 (2006.01)

Patent

CA 2123865

Abstract The present invention provides a method of producing a biologically active polypeptide by culturing animal cells capable of producing the polypeptide, adapted to agitation culture in suspension in serum-free medium, and Chinese hamster ovarian cells, capable of proliferation in suspension in serum-free medium, which produce a polypeptide belonging to the human nerve growth factor family and is useful for industrial mass production of a biologically active polypeptide in high purity.

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