Systematic evolution of ligands by exponential enrichment:...

Details Systematic evolution of ligands by exponential enrichment:... Systematic evolution of ligands by exponential enrichment:...

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) C07H 21/04 (2006.01) C12N 15/10 (2006.01) C12Q 1/68 (2006.01) C12P 19/34 (2006.01)

Patent

CA 2645735

This invention discloses high-affinity oligonucleotide ligands to complex tissue targets, specifically nucleic acid ligands having the ability to bind to complex tissue targets, and the methods for obtaining such ligands. Tissue targets comprise cells, subcellular components, aggregates or cells, collections of cells, and higher ordered structures. Specifically, nucleic acid ligands to red blood cells ghosts, glioblastomas, and lymphomas are described.

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