Pyrazolopyrimidines and related heterocycles as kinase...

Details Pyrazolopyrimidines and related heterocycles as kinase... Pyrazolopyrimidines and related heterocycles as kinase...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01)

Patent

CA 2762313

The invention provides compounds of general formula (I) that inhibit selected kinases (Pim and/or CK2 kinases) and compositions containing such compounds. These compounds and compositions are useful for treating proliferative disorders such as cancer, as well as other kinase-associated conditions including inflammation, pain, and certain infections and immunological disorders.

L'invention porte sur des composés de formule générale (I) qui inhibent des kinases sélectionnées (des kinases Pim et/ou CK2) et sur des compositions contenant de tels composés. Ces composés et compositions sont utiles pour le traitement de troubles prolifératifs tels que le cancer, ainsi que d'autres états associés à la kinase, comprenant une inflammation, une douleur et certaines infections et certains troubles immunologiques.

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