Prophylactic and therapeutic influenza vaccines, antigens,...

A - Human Necessities – 61 – K

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A61K 39/145 (2006.01)

Patent

CA 2696764

The present invention relates to the intersection of the fields of immunology and protein engineering, and particularly to antigens and vaccines useful in prevention of infection by influenza virus. Provided are recombinant protein antigens, compositions, and methods for the production and use of such antigens and subunit vaccine compositions. In some embodiments, influenza antigens include hemagglutinin polypeptides neuraminidase polypeptides, and/or combinations thereof.

La présente invention concerne le croisement des domaines de l'immunologie et du génie protéique, et, plus particulièrement, des antigènes et vaccins utiles pour la prévention d'infections par le virus de la grippe. La présente invention concerne des antigènes de protéine recombinante, des compositions et des procédés pour la production et l'utilisation de tels antigènes et de compositions de vaccin sous-unités. Selon certains modes de réalisation de la présente invention, des antigènes de la grippe comprennent des polypeptides d'hémagglutinine, des polypeptides de neuraminidase et/ou des combinaisons de ceux-ci.

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