New polynucleotides and polypeptides of the ifn alpha-21 gene

Details New polynucleotides and polypeptides of the ifn alpha-21 gene New polynucleotides and polypeptides of the ifn alpha-21 gene

Category

C - Chemistry, Metallurgy

Subcategory

07

Subsubcategory

K

IPC codes

C07K 14/56 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12N 15/10 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01) A61K 39/00 (2006.01)

Type

Patent

Patent number

CA 2442775

Description

The present invention relates to new polynucleotides derived from the nucleotide sequence of the IFN.alpha.-21 gene comprising new SNPs, and new polypeptides derived from the natural wild-type IFN.alpha.-21 protein comprising at least one mutation caused by at least one SNP of the invention as well as their therapeutic uses.

La présente invention concerne de nouveaux polynucléotides dérivés de la séquence nucléotidique du gène IFN.alpha.-21 comprenant de nouveaux SNP (polymorphismes nucléotidiques simples). Cette invention concerne aussi de nouveaux polypeptides dérivés de la protéine naturelle IFN.alpha.-21 de type naturelle comprenant au moins une mutation causée par au moins un SNP de l'invention, ainsi que des utilisations thérapeutiques de ceux-ci.

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