Treatment of inflammatory diseases

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/133 (2006.01) A61K 31/138 (2006.01) A61K 31/4245 (2006.01) A61K 31/661 (2006.01) A61K 45/06 (2006.01) A61P 25/00 (2006.01) A61P 25/02 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2660880

The present invention relates generally to the field of inflammatory diseases of the peripheral nervous system. More particularly, it concerns methods for treating inflammatory diseases of the peripheral nervous system by modulating sphingosine-1- phosphate receptor activity. In one embodiment, the present invention provides a method of treating a subject with chronic inflammatory demyelinating polyneuropathy (CIDP) or other autoimmune neuropathies comprising administering to the subject an effective amount of FTY720.

L'invention porte d'une manière générale sur le domaine de maladies inflammatoires du système nerveux périphérique, et plus particulièrement sur le traitement de maladies inflammatoires du système nerveux périphérique par modulation de l'activité du récepteur de la sphingosine-1- phosphate. Dans une exécution, l'invention porte sur une méthode de traitement d'un sujet atteint de polyneuropathie démyélinisante inflammatoire chronique (CIDP) ou d'autres neuropathies autoimmunes, consistant à lui administrer une dose efficace de FTY720.

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