Use of targeted oxidative therapeutic formulation in...

A - Human Necessities – 61 – K

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A61K 47/18 (2006.01) A61K 47/10 (2006.01) A61K 47/22 (2006.01)

Patent

CA 2566190

A pharmaceutical formulation and its use. The pharmaceutical formulation contains peroxidic species or reaction products resulting from oxidation of an alkene, such as geraniol, by an oxygen-containing oxidizing agent, such as ozone; a penetrating solvent, such as dimethylsulfoxide ("DMSO"); a dye containing a chelated metal, such as hematoporphyrin; and an aromatic redox compound, such as benzoquinone. The pharmaceutical formulation is used to effectively treat patients affected with age-related macular degeneration ("ARMD").

L'invention concerne une formulation pharmaceutique et l'utilisation de celle-ci. La formulation pharmaceutique contient des espèces peroxydiques ou des produits de réaction résultant de l'oxydation d'un alcène, tel que le géraniol, par un agent oxydant contenant de l'oxygène, tel que l'ozone; un solvant pénétrant tel que le diméthylsulfoxyde ("DMSO"); un colorant contenant un métal chélaté tel que l'hématoporphyrine; et un composé redox aromatique tel que la benzoquinone. Cette formulation pharmaceutique permet de traiter efficacement les patients atteints de dégénérescence maculaire liée à l'âge.

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