Nuclear matrix protein alterations associated with colon...

Details Nuclear matrix protein alterations associated with colon... Nuclear matrix protein alterations associated with colon...

C - Chemistry, Metallurgy

07

K

C07K 14/705 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2473994

Proteins useful in the diagnosis of proliferative disorders of the colon are present in nuclear matrix protein preparations and can be characterized by molecular weight, isoelectric point, and amino acid sequence. The proteins may be identified, for example, by 2D-gel electrophoresis or by specific binding partners, such as antibodies.

L'invention concerne des protéines utiles dans le diagnostic de troubles prolifératifs du colon, présentes dans des préparations de protéine de matrice nucléaire, et pouvant être caractérisées par leur poids moléculaire, leur point isoélectrique et leur séquence d'aminoacides. Lesdites protéines peuvent être identifiées, par exemple, par gel d'électrophorèse 2D ou par des partenaires spécifiques de liaison, de type anticorps.

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