System for filling and assembling pharmaceutical delivery...

A - Human Necessities – 61 – M

Patent

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Details

A61M 5/24 (2006.01) A61J 1/00 (2006.01) A61J 1/06 (2006.01) A61L 2/07 (2006.01) A61L 2/20 (2006.01) B65B 3/00 (2006.01)

Patent

CA 2505162

A system is provided which permits syringe barrels of prefilled disposable syringes to be filled and capped on standard vial filling equipment, and which permits the syringe body and piston comprising the barrel to be simultaneously sterilized by a sterilizing gas. The system provides means for stabilizing syringe barrels so they can be conveyed upright on their bases without tipping through vial filling and capping equipment. Preferably, the stabilizing means comprises a cylindrical sleeve into which the lower end of the syringe body is inserted, thereby stably supporting it against tipping. The system also provides means by which the piston is retained in close proximity to the lower end of the syringe body, but slightly separated therefrom to permit access to all surfaces of the piston by a sterilizing gas. Preferably, the piston is retained directly below the lower end of the syringe body, and substantially centred therewith, to permit the piston to be inserted into the lower end of the body merely by pushing the body and piston together.

L'invention concerne un système qui permet de remplir et de fermer des cylindres de seringues jetables pré-remplies sur un équipement de remplissage de flacons standard, ce système permettant de stériliser simultanément au moyen d'un gaz stérilisant le corps de la seringue et le piston comprenant le cylindre. Ce système comprend un dispositif pour stabiliser les cylindres de seringues, de sorte qu'ils sont transportés droits sur leur base, sans basculer dans l'équipement de remplissage et de fermeture de flacons. Le dispositif de stabilisation comporte de préférence un manchon cylindrique dans lequel la partie inférieure du corps de la seringue est insérée pour le stabiliser contre le basculement. Ce système est également pourvu de dispositifs qui retiennent le piston à proximité étroite de la partie inférieure du corps de la seringue, tout en le maintenant légèrement séparé de celle-ci, afin que le gaz stérilisant puisse accéder à toutes les surfaces du piston. Le piston est de préférence retenu directement sous la partie inférieure du corps de la seringue, et sensiblement centré relativement à celui-ci, pour permettre au piston d'être inséré dans la partie inférieure du corps de la seringue par simple mouvement de pression sur le corps et le piston simultanément.

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