Method for detecting ovarian cancer based on human...

Details Method for detecting ovarian cancer based on human... Method for detecting ovarian cancer based on human...

G - Physics

01

N

G01N 33/574 (2006.01) C07K 14/47 (2006.01) C12N 9/64 (2006.01)

Patent

CA 2426286

A method for the diagnosis, prognosis, and monitoring of ovarian cancer in a subject by detecting hK6 in a sample from the subject, preferably a serum sample or tumor tissue extract. hK6 may be measured using a reagent that detects or binds to hK6 preferably antibodies specifically reactive with hK6 or a part thereof. Imaging methods for tumors associated with hK6 are also described using an agent that binds to hK6 which has a label for imaging the tumor.

L'invention concerne une méthode qui permet de diagnostiquer, prronostiquer et surveiller le cancer de l'ovaire chez un sujet, par détection du gène hK6 dans un échantillon prélevé chez le sujet, de préférence dans un échantillon sérique ou dans un échantillon de tissu cancéreux. Le gène hK6 peut être mesuré au moyen d'un réactif qui détecte hK6 ou se lie à lui, de préférence des anticorps qui réagissent spécifiquement à hK6 ou à une partie de hK6. L'invention concerne également des méthodes de prise d'images de tumeurs associées à hK6, qui utilisent un agent de fixation à hK6, lequel comporte un marqueur permettant de présenter en images la tumeur.

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