Anti-viral and anti-cancer agents

Details Anti-viral and anti-cancer agents Anti-viral and anti-cancer agents

A - Human Necessities

61

K

A61K 31/19 (2006.01) A61K 31/04 (2006.01) A61K 31/05 (2006.01) A61K 31/06 (2006.01) A61K 31/085 (2006.01) A61K 31/135 (2006.01) A61K 31/165 (2006.01) A61K 31/185 (2006.01) A61K 31/192 (2006.01) A61K 38/06 (2006.01) C07C 63/70 (2006.01) C07C 205/06 (2006.01) C07C 205/12 (2006.01) C07C 205/24 (2006.01) C07C 205/37 (2006.01) C07C 205/57 (2006.01) C07C 205/58 (2006.01) C07C 205/60 (2006.01) C07C 211/52 (2006.01) C07C 237/30 (2006.01) C07C 309/39 (2006.01) C07C 309/40 (2006.01) C07C 309/46 (2006.01) C07K 5/02 (2

Patent

CA 2185817

2-Chloro-5 nitrobenzoic acid and various other chloro and nitro substitute benzoic acid derivatives are disclosed for administration in tablet or injectable solution form for the prophylaxis and therapy of neoplasm or viral infection. The active compounds have surprising efficacy in various treatment regimes and have particular application to HIV-infection and demonstrate various beneficial effects, including regression of lesions in HIV-related Kaposi's sarcoma.

L'invention se rapporte à l'acide 2-chloro-5-nitrobenzoïque et à divers autres dérivés de l'acide benzoïque à substitution chloro et nitro, ces acides étant administrés sous forme de comprimés ou de solutions injectables, pour la prophylaxie et la thérapie des néoplasmes ou des infections virales. Les composés actifs ont une étonnante efficacité dans divers schémas thérapeutiques et s'appliquent notamment aux infections dues au VIH et présentent divers effets bénéfiques, y compris la régression de lésions dans la maladie de Kaposi associée au VIH.

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