Fungal stress proteins

Details Fungal stress proteins Fungal stress proteins

C - Chemistry, Metallurgy

12

N

167/129, 530/13,

C12N 15/31 (2006.01) A61K 39/00 (2006.01) C07K 7/04 (2006.01) C07K 14/37 (2006.01) C07K 14/40 (2006.01) C07K 16/14 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2034504

4 polypeptide sequence from Candida albicans is described which has significant sequence homology with known stress proteins from other organisms, particularly the heat shock protein hsp 90 of Sacchromyces cerevisiae. Corresponding DNA se- quences are also described, together with antibodies raised against fragments of the sequence. The polypeptide and DNA se- quences and antibodies provide separate means for the diagnosis and/or treatment of fungal, particularly Candida, infections.

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