A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/365 (2006.01) A61K 31/36 (2006.01) A61P 3/10 (2006.01) A61P 9/10 (2006.01) A61P 15/18 (2006.01)
Patent
CA 2638124
There is disclosed use of certain cyclolignans for prophylaxis or treatment of diabetes mellitus type 2, nephropathy, retinopathy, macular degeneration, retinopathy of prematurity, central retinal vein occlusion, branch retinal vein occlusion, rubeotic glaucoma, thyroid eye disease, corneal graft rejection and corneal chemical burns; and for contraception. Preferred compounds are picropodophyllin, deoxypicropodophyllin and anhydropicropodo- phyllol. There is also described a method of treatment of an eye disease.
Cette invention porte sur l'utilisation de certains cyclolignans dans la prophylaxie ou le traitement du diabète de type 2, la néphropathie, la rétinopathie, la dégénérescence maculaire, la rétinopathie de prématurité, l'occlusion de la veine centrale de la rétine, l'occlusion de la veine de dérivation de la rétine, le glaucome de la rubéole, la maladie de Graves-Basedow, le rejet du greffon cornéen et la brûlure chimique de la cornée. Certains cyclolignans sont également utiliés dans la contraception. Des composés préférés des cyclolignans sont la picropodophylline, la désoxypicropodophylline et l'anhydropicropodo-phyllol. L'invention porte également sur une méthode de traitement d'une maladie de l'oeil.
Axelson Magnus
Danielsson Olof
Economou Mario-Alexander
Larsson Olle
Axelar Ab
Fetherstonhaugh & Co.
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