Therapeutic agent for urinary excretion disorder

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/426 (2006.01) A61P 13/00 (2006.01) A61P 13/02 (2006.01) C07D 277/36 (2006.01)

Patent

CA 2677769

Disclosed is an EP1 antagonist, particularly a compound represented by the general formula (I), a salt thereof, a solvate of the compound or the salt, or a prodrug of the compound, the salt or the solvate. The compound is effective for the prevention or treatment of urinary excretion disorder and/or the amelioration of a condition associated with urinary excretion disorder (e.g., slowing of urinary stream, division of urinary stream, interruption of urinary stream, delayed urination, straining at urination, terminal dribbling). (I) wherein all symbols are as defined in the description.

L'invention concerne un antagoniste de EP1, en particulier un composé représenté par la formule générale (I), un sel de celui-ci, un solvate du composé ou du sel, ou un promédicament du composé, du sel ou du solvate. Le composé est efficace pour la prévention ou le traitement de trouble de la miction et/ou l'amélioration d'une condition associée au trouble de la miction (par exemple, ralentissement du flux urinaire, division du flux urinaire, interruption du flux urinaire, miction retardée, effort à la miction, égouttement terminal). (I) dans laquelle tous les symboles sont tels que définis dans la description.

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