Substituted 3-cyanothiophene acetamides as glucagon receptor...

Details Substituted 3-cyanothiophene acetamides as glucagon receptor... Substituted 3-cyanothiophene acetamides as glucagon receptor...

C - Chemistry, Metallurgy

07

D

C07D 333/38 (2006.01) A61K 31/381 (2006.01) A61K 31/4365 (2006.01) A61P 3/10 (2006.01) C07D 211/00 (2006.01) C07D 311/00 (2006.01) C07D 333/00 (2006.01) C07D 333/78 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2521732

The present invention relates to compounds of formula (I) wherein RI, R2, R3, R4 and n are as defined in the description and claims, and pharmaceutically acceptable salts thereof The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with the antagonism of the glucagon receptor, such as diabetes.

La présente invention a trait à des composés de formule (I), dans laquelle : R1, R2, R3, R4 et n sont tels que définis dans la description et dans les revendications, et leurs sels pharmaceutiquement acceptables. Les composés sont utiles pour la traitement et/ou la prophylaxie de maladies associées à l'antagonisme du récepteur de glucagon, telles que le diabète.

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