Nf-kb inhibitors and uses thereof

Details Nf-kb inhibitors and uses thereof Nf-kb inhibitors and uses thereof

C - Chemistry, Metallurgy

07

D

C07D 233/28 (2006.01) A61K 31/4164 (2006.01)

Patent

CA 2652343

A diastereomers of imidazolines as 4-position acids are described. The imidazoline diastereomers potentiate the activity of antitumor drugs and are potent inhibitors of the transcription factor NF-.kappa.B.

L'invention concerne des diastéréomères d'imidazolines utilisés comme acides en position 4. Ces diastéréomères d'imidazolines renforcent l'activité de médicaments antitumoraux et sont de puissants inhibiteurs du facteur de transcription NF-.kappa.B.

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