New 4-arylpiperidine derivatives for the treatment of pruritus

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 401/04 (2006.01) A61K 31/454 (2006.01) A61K 31/4709 (2006.01) A61K 31/4725 (2006.01) A61K 31/498 (2006.01) A61K 31/502 (2006.01) A61K 31/517 (2006.01) A61P 1/10 (2006.01) A61P 17/04 (2006.01) C07D 211/26 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2309505

There is provided a compound of formula I, (see formula I) wherein Het1, T, X, R1, R2 and R3 have meanings given in the description, which are useful in the prophylaxis and in the treatment of diseases mediated by opiate receptors, such as pruritus.

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