Methods of quantitation and identification of peptides and...

G - Physics – 01 – N

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G01N 33/68 (2006.01) G01N 33/543 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2507864

The present invention provides methods of quantifying the amount or concentration of one or more peptides and/or proteins in one or more samples using matrix-assisted laser desorption/ionization (MALDI) mass spectrometry to detect differentially isotopically-labeled peptides and/or proteins. The invention also provides methods of identifying one or more peptides and/or proteins in one or more samples.

La présente invention concerne des méthodes de quantification de la quantité ou de la concentration d'au moins un peptide et/ou d'au moins une protéine dans au moins un échantillon au moyen de protéines et/ou de peptides étiquetés différentiellement de manière isotope. Cette invention a également trait à des méthodes d'identification d'au moins un peptide et/ou d'au moins une protéine dans au moins un échantillon.

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