C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 307/58 (2006.01) A61K 31/34 (2006.01) A61K 31/365 (2006.01) A61K 31/38 (2006.01) A61K 31/395 (2006.01) A61K 31/66 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) C07C 311/29 (2006.01) C07C 311/49 (2006.01) C07C 311/51 (2006.01) C07C 317/24 (2006.01) C07D 307/33 (2006.01) C07D 405/04 (2006.01) C07D 407/04 (2006.01) C07D 409/04 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01) C07D 503/04 (2006.01) C07F 9/547 (2006.01)
Patent
CA 2176974
Compounds useful in the treatment of cyclooxygenase-2 mediated diseases are provided of formula (I): (see fig. I) wherein R1 is selected from the group consisting of (a) S(O)2CH3, and (b) S(O)2NH2, and R2 is unsubstituted, mono or di- substituted phenyl wherein the substituents are selected from the group consisting of halo, methoxy, methyl, said halo being selected from the group consisting of fluoro, chloro and bromo.
Ducharme Yves
Gauthier Jacques Yves
Leblanc Yves
Leger Serge
Prasit Petpiboon
Merck Frosst Canada Inc.
Merck Frosst Company
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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