Thieno [2,3-d] pyrimidine compounds as inhibitors of...

Details Thieno [2,3-d] pyrimidine compounds as inhibitors of... Thieno [2,3-d] pyrimidine compounds as inhibitors of...

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/519 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2595882

Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I): wherein A1, A2, A3, A4, A5, A6, A7, A8, X4, X6, R2, R4, R5, and R6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

L'invention concerne des composés et des sels de ceux-ci pharmaceutiquement acceptables. Ces composés sont représentés par la formule (I) dans laquelle A1, A2, A3, A4, A5, A6, A7, A8, X4, X6, R2, R4, R5 et R6 sont tels que définis dans la description de l'invention. L'invention concerne également des compositions pharmaceutiques correspondantes, des méthodes de traitement, des méthodes de synthèse et des intermédiaires.

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