Therapeutic combination comprising a nmda receptors blocker...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/165 (2006.01) A61K 31/135 (2006.01) A61K 31/4468 (2006.01) A61K 31/485 (2006.01) A61K 45/06 (2006.01) A61P 25/04 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2616659

The invention relates to a medicament comprising a combination of a substance that blocks both the ion channel associated to NMDA receptors and MAO enzymes and a narcotic analgesic substance, preferably a fixed combination, pharmaceutical compositions thereof, and to the use thereof for the treatment of subjects suffering of various types of pain and/or for inhibiting the development of tolerance, and/or physical dependence on a narcotic analgesic substance.

La présente invention se rapporte à un médicament comprenant la combinaison d~une substance qui bloque à la fois le canal ionique associé aux récepteurs NMDA et les enzymes MAO et une substance analgésique narcotique, de préférence une combinaison fixe, ses compositions pharmaceutiques, et à son utilisation pour le traitement de sujets souffrant de divers types de douleur et/ou pour inhiber le développement de la tolérance et/ou de la dépendance physique à une substance analgésique narcotique.

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