Inhibitors of membrane type-1 matrix metalloproteinase for...

A - Human Necessities – 61 – K

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A61K 38/00 (2006.01) A61K 31/19 (2006.01)

Patent

CA 2638816

Provided herein are compositions and methods for inhibiting the transmigration of T cells through pancreatic capillary endothelium and treating insulin- dependent diabetes mellitus (IDDM; type I diabetes) using inhibitors of MTl- MMP.

La présente invention concerne des compositions et des procédés d'inhibition de la transmigration de cellules T à travers l'endothélium capillaire pancréatique et le traitement du diabète sucré qui dépend de l'insuline (IDDM, diabète de type I) à l'aide d'inhibiteurs de MTl-MMP.

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