Biomarker

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2747760

Described are bladder cancer specific biomarkers and lung cancer specific biomarkers comprising the nucleic acid sequence of the Engrailed-2 (EN2) gene or the amino acid sequence of the encoded EN2 protein. Also described are uses of the biomarkers in the treatment, diagnosis, monitoring and imaging of bladder cancer and lung cancer.

L'invention concerne des marqueurs biologiques spécifiques du cancer de la vessie et des marqueurs biologiques spécifiques du cancer du poumon comprenant la séquence d'acide nucléique du gène Engrailed-2 (EN2) ou la séquence d'acides aminés de la protéine EBN2 codée. Elle concerne également des utilisations des marqueurs biologiques dans le traitement, le diagnostic, le suivi et l'imagerie du cancer de la vessie et du cancer du poumon.

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