Oil in water emulsions containing saponins

Details Oil in water emulsions containing saponins Oil in water emulsions containing saponins

A - Human Necessities

61

K

A61K 9/107 (2006.01) A61K 39/00 (2006.01) A61K 39/015 (2006.01) A61K 39/29 (2006.01) A61K 39/39 (2006.01)

Patent

CA 2302554

The present invention relates to an oil in water emulsion vaccine composition. In particular, the present invention relates to a vaccine adjuvant formulation based on oil in water emulsion comprising a metabolisable oil and a saponin, wherein the oil and a saponin are present in a ratio of between 1:1 and 200:1. The invention further relates to methods for preparing the emulsion and its use in medicine.

L'invention concerne une composition de vaccin à base d'une émulsion huile-dans-eau. Elle concerne, en particulier, une formulation d'adjuvant de vaccin à base d'une émulsion huile-dans-eau contenant une huile métabolisable et une saponine, l'huile et la saponine étant présentes selon un rapport situé entre 1:1 et 200:1. Elle concerne, de plus, des procédés servant à préparer cette émulsion et son utilisation en médecine.

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