Heteroarylnaphthalene lactones as inhibitors of leukotriene...

Details Heteroarylnaphthalene lactones as inhibitors of leukotriene... Heteroarylnaphthalene lactones as inhibitors of leukotriene...

C - Chemistry, Metallurgy

07

D

C07D 405/14 (2006.01) A61K 31/365 (2006.01) A61K 31/38 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/70 (2006.01) C07D 407/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 493/08 (2006.01) C07H 7/04 (2006.01)

Patent

CA 2143220

Compounds having formula (I): are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.

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