Indole derivatives and their use as 15-lipoxygenase inhibitors

Details Indole derivatives and their use as 15-lipoxygenase inhibitors Indole derivatives and their use as 15-lipoxygenase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 209/14 (2006.01) A61K 31/404 (2006.01) A61P 43/00 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2411116

This invention provides indole and benzimidazole 15-lipoxygenase (15-LO) inhibitors of the formula where one of Y1 and Y2 is CH, N, or NH, and the other is R3 includes H, halo, HN2, COOH, alkyl; R4 includes halo, alkyl, and alkoxy; Z is C, CH, or NR5; R5 is H or oxycabonyl; and each X is independently H, alkyl, alkoxy, or halo.

L'invention concerne des indols et des benzimidazoles constituant des inhibiteurs de 15-lipoxygénase (15-LO), qui correspondent à la formule (I), dans laquelle: un des symboles Y¿1? et Y¿2? représente CH, L ou bien NH, et l'autre représente (a) ou (b), R¿3? peut être H, halo, NH¿2?, COOH ou alkyle; R¿4? peut être halo, alkyle ou alcoxy; Z représente C, CH ou NR¿5?; R¿5? représente H ou oxycarbonyle; et les X représentent, indépendamment l'un de l'autre, H, alkyle, alcoxy ou halo.

Affiliated with

Also associated with

Rating

Indole derivatives and their use as 15-lipoxygenase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Indole derivatives and their use as 15-lipoxygenase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Indole derivatives and their use as 15-lipoxygenase inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1587872